Prenylated flavonoids from Glycyrrhiza uralensis as promising anti-cancer agents: a preliminary structure-activity study

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Chemical profile and anti-inflammatory activity of total flavonoids from Glycyrrhiza uralensis Fisch.

Glycyrrhiza uralensis Fisch. (G. uralensis) is one of the most widely used herbal medicines for the treatment of cough, spasms, pain, inflammation and low immunity This study was designed to enrich total flavonoids (TFF) from G. uralensis and investigate the anti-inflammatory activity of TFF. The anti-inflammatory activity was evaluated by inflammatory models of dimethylbenzene (DMB)-induced ea...

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Chemical profile and anti-inflammatory activity of total flavonoids from Glycyrrhiza uralensis Fisch.

Glycyrrhiza uralensis Fisch. (G. uralensis) is one of the most widely used herbal medicines for the treatment of cough, spasms, pain, inflammation and low immunity This study was designed to enrich total flavonoids (TFF) from G. uralensis and investigate the anti-inflammatory activity of TFF. The anti-inflammatory activity was evaluated by inflammatory models of dimethylbenzene (DMB)-induced ea...

متن کامل

Antibacterial compounds from Glycyrrhiza uralensis.

From the roots of Glycyrrhiza uralensis, two new pterocarpenes, glycyrrhizol A (1) and glycyrrhizol B (2), along with four known isoflavonoids, 5-O-methylglycryol (3), isoglycyrol (4), 6,8-diisoprenyl-5,7,4'-trihydroxyisoflavone (5), and gancaonin G (6), were isolated using a bioassay-guided fractionation method. The structures of the new compounds (1and 2) were elucidated by spectroscopic data...

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Optimized Extraction, Preliminary Characterization, and In Vitro Antioxidant Activity of Polysaccharides from Glycyrrhiza Uralensis Fisch

BACKGROUND This study performed optimized extraction, preliminary characterization, and in vitro antioxidant activities of polysaccharides from Glycyrrhiza uralensis Fisch. MATERIAL AND METHODS Three parameters (extraction temperature, ratio of water to raw material, and extraction time) were optimized for yields of G. uralensis polysaccharides (GUP) using response surface methodology with Box-...

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Aldose reductase inhibitory compounds from Glycyrrhiza uralensis.

We evaluated the inhibitory effects of components from the root of Glycyrrhiza uralensis (G. uralensis) on aldose reductase (AR) and sorbitol formation in rat lenses with high levels of glucose as part of our ongoing search of natural sources for therapeutic and preventive agents for diabetic complications. In order to identify the bioactive components of G. uralensis, 5 prenylated flavonoids (...

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ژورنال

عنوان ژورنال: Journal of Chinese Pharmaceutical Sciences

سال: 2016

ISSN: 1003-1057

DOI: 10.5246/jcps.2016.01.003